Kuwait-University-Journal-of-Law-header
Search
Kuwait Journal of Science

Previous Issues

Advance Search
Year : From To Vol
Issue Discipline:
Author

Volume :24 Issue : 2 1997      Add To Cart                                                                    Download

The effect of denervation and immobilization on the hindlimb muscles of the jerboa (Jaculus jaculus)

Auther : M. A. AL-WOHAIB AND M. A. ALNAQEEB

 Department of Zoology, University of Kuwait, P0 Box 5969, Safat 13060, Kuwait

 ABSTRACT

Among the different factors that influence the skeletal muscle properties and atrophic state are contractile activity and muscle neural supply. Accordingly the effects of denervation and immobilization have been studied on the extensor digitorum longus (EDL) and soleus muscle of the hindlimb of the jerboa (Jaculus jaculus). Muscle weight, total fiber number, number of different fiber types and fiber diameters of the two muscles were measured. The EDL and soleus muscles of denervated and immobilized animals were compared with those of controls. Both denervated EDL and soleus muscles showed more reduction in weight compared with immobilized muscles and controls. Following denervation, the reduction in the diameters of type IIB fibers in the EDL was more than that of type hA fibers, which indicated that type IIB fibers are in greater need of neural control than type IIA fibers. The degree of atrophy in type IIA and IIB fibers was more extensive after denervation than after immobilization. Type fibers comprising the soleus muscle were also significantly reduced in diameter after dener vation. Similarly, type I fibers in the soleus muscle were reduced in diameter more after denervation than after immobilization. The above results demonstrated that both neural innervation and activity influence jerboa muscle growth and differentiation. It is proposed it that Jaculus jaculus is a good animal model system for studying the effects of activity or lack of activity on mammalian skeletal muscle.

Kuwait Journal of Science
Journal of Law

You are Visitor No.

55170

Journal of Law
Journal of Law
Tell your friendsJournal of Law
Journal of Law

Last Updated

Jun 19, 2012

Journal of Law
Journal of Law
Journal of Law

Please enter your email Here to receive our news

Journal of Law